Product Name :DNMT3A polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB,1:500 - 1:2000
Background :CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DNMT3A;DNMT3A2;M.HsaIIIA;TBRS;DNMT3A
Immunogen :Recombinant fusion protein of human DNMT3A(NP_715640.2).
Modification :Unmodification