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MMP13 polyclonal antibody

货号: BS79990

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79990

Product Name :MMP13 polyclonal antibody

Swiss-Prot :P45452

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP13 polyclonal antibody detects endogenous levels of MMP13 protein.

BiowMW :~ 53, 34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MMP13;CLG3;MANDP1;MDST;MMP-13

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MMP13.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MMP13 expression in HEK293T (A), Hela (B), mouse lung (C), rat lung (D) whole cell lysates.

Immunohistochemical analysis of MMP13 staining in human breast cancer formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of MMP13 staining in HeLa cells.

免疫沉淀（IP）