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LRP6 polyclonal antibody

货号: BS79947

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS79947

Product Name :LRP6 polyclonal antibody

Swiss-Prot :O75581

Host :Rabbit

Reactivity :Human

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LRP6;ADCAD2;STHAG7

Immunogen :Recombinant fusion protein of human LRP6(NP_002327.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of U2OS cells using LRP6 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.