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DNASE1 polyclonal antibody

货号: BS79901

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79901

Product Name :DNASE1 polyclonal antibody

Swiss-Prot :P24855

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :Refer to Figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DNASE1;DNL1;DRNI

Immunogen :Recombinant fusion protein of human DNASE1(NP_005214.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of C6 cells using DNASE1 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of NIH-3T3 cells using DNASE1 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）