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MBTPS1 polyclonal antibody

货号: BS79814

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79814

Product Name :MBTPS1 polyclonal antibody

Swiss-Prot :Q14703

Host :Rabbit

Reactivity :Human

Applications :IHC, IF/ICC

Application_all :IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MBTPS1;PCSK8;S1P;SKI-1

Immunogen :Recombinant fusion protein of human MBTPS1(NP_003782.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded human colon cancer using MBTPS1 antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded human colon using MBTPS1 antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded human stomach using MBTPS1 antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunofluorescence analysis of U2OS cells using MBTPS1 antibody . Blue: DAPI for nuclear staining.