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FAK polyclonal antibody

货号: BS79679

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79679

Product Name :FAK polyclonal antibody

Swiss-Prot :Q05397

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:1000 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200

Background :This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :125KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2

Immunogen :Recombinant fusion protein of human FAK(NP_722560.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded mouse brain using FAK Rabbit pAb at dilution of 1:100 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

Immunofluorescence analysis of NIH-3T3 cells using FAK Rabbit pAb at dilution of 1:100 . Blue: DAPI for nuclear staining.