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β-Catenin polyclonal antibody

货号: BS79675

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79675

Product Name :β-Catenin polyclonal antibody

Swiss-Prot :P35222

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IP

Application_all :WB,1:500 - 1:1000|IHC,1:50 - 1:100|IP,1:10 - 1:50

Background :The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :β-Catenin polyclonal antibody detects endogenous levels of β-Catenin protein.

BiowMW :~ 85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CTNNB;MRD19;armadillo;beta Catenin;CTNNB1

Immunogen :A synthetic peptide of human β-Catenin(NP_001895.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of β-Catenin expression in mouse brain (A), C6 (B), CHOK1 (C), Hela (D) whole cell lysates.

Immunohistochemical analysis of β-Catenin staining in human cholangiocarcinoma formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）