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PINK1 polyclonal antibody

货号: BS79658

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS79658

Product Name :PINK1 polyclonal antibody

Swiss-Prot :Q9BXM7

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC IF

Application_all :WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Background :PTEN induced putative kinase 1, PINK1, is a mitochondrial serine/threonine kinase involved in the normal function and integrity of mitochondria, as well as in reduction of cytochrome c release from mitochondria. PINK1 phosphorylates Parkin and promotes its translocation to mitochondria. Research studies have shown that mutations in PINK1 are linked to autosomal recessive early onset Parkinson’s disease, and are associated with loss of protective function, mitochondrial dysfunction, aggregation of α-synuclein, as well as proteasome dysfunction.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PINK1 polyclonal antibody detects endogenous levels of PINK1 protein.

BiowMW :~ 60 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serine/threonine-protein kinase PINK1 mitochondrial; BRPK; PTEN-induced putative kinase protein 1

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PINK1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PINK1 expression in HEK293T (A), MCF7 (B), HCT116 (C), mouse heart (D), rat testis (E) whole cell lysates.

Immunohistochemical analysis of PINK1 staining in human colorectal cancer formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）