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PPARγ polyclonal antibody

货号: BS79617

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79617

Product Name :PPARγ polyclonal antibody

Swiss-Prot :P37231

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, IF/ICC

Application_all :WB,1:500 - 1:1000|IHC,1:100 - 1:200|IF/ICC,1:100 - 1:500

Background :This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PPARγ Polyclonal Antibody detects endogenous levels of PPARγ protein.

BiowMW :57KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIMT1;GLM1;NR1C3;PPARG1;PPARG2;PPARgamma;PPAR gamma;PPARG

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PPAR gamma.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of PPAR gamma expression in Hela (A), rat ovary (B), mouse spleen (C), LO2 (D) whole cell lysates.

Immunohistochemical analysis of PPAR gamma staining in human colon formalin fixed paraffin embedded tissue section.

Immunofluorescent analysis of PPAR gamma staining in MCF7 cells.

SOX4 facilitates brown fat development and maintenance through EBF2-mediated thermogenic gene program in mice

Journal10.1038/s41418-024-01397-0

ApplicationWB

IF13.7

SpeciesMouse

PMID39402212