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SOCS3 polyclonal antibody

货号: BS79571

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS79571

Product Name :SOCS3 polyclonal antibody

Swiss-Prot :O14543

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:1000|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SOCS3 polyclonal antibody detects endogenous levels of SOCS3 protein.

BiowMW :24KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SOCS3;ATOD4;CIS3;Cish3;SOCS-3;SSI-3;SSI3

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SOCS3.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of SOCS3 expression in U87MG (A), HEK293T (B) whole cell lysates.

Immunofluorescent analysis of SOCS3 staining in A2780 cells.

免疫沉淀（IP）

免疫组织化学（IHC）