Product Name :Phospho-FAK-Y925 polyclonal antibody
Application_all :WB,1:500 - 1:2000
Background :This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015]
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Phosphorylated
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;PTK2
Immunogen :A synthetic phosphorylated peptide around Y925 of human FAK(NP_722560.1).
Modification :Phosphorylated
