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Complement C4A polyclonal antibody

货号: BS79235
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS79235
Product Name :Complement C4A polyclonal antibody
Swiss-Prot :P0C0L4
Host :Rabbit
Reactivity :Human
Applications :WB
Application_all :WB,1:500 - 1:2000
Background :This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
BiowMW :192kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :C4A;C4;C4A2;C4A3;C4A4;C4A6;C4AD;C4S;CO4;CPAMD2;RG
Immunogen :Recombinant fusion protein of human Complement C4A(NP_009224.2).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of HepG2 cells, using Complement C4A antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com