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DROSHA polyclonal antibody

货号: BS79052
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS79052
Product Name :DROSHA polyclonal antibody
Swiss-Prot :Q9NRR4
Host :Rabbit
Reactivity :Human, Mouse
Applications :WB
Application_all :WB,1:500 - 1:2000
Background :This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
BiowMW :159KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :DROSHA;ETOHI2;HSA242976;RANSE3L;RN3;RNASE3L;RNASEN
Immunogen :A synthetic peptide of human DROSHA(NP_037367.3).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of Mouse heart, using DROSHA Rabbit pAb at 1:500 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 180s.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com