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CLDN4 polyclonal antibody

货号: BS78406

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS78406

Product Name :CLDN4 polyclonal antibody

Swiss-Prot :O14493

Host :Rabbit

Reactivity :Human

Applications :WB, IHC

Application_all :WB,1:500 - 1:2000|IHC,1:25 - 1:100

Background :The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :22kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLDN4;CPE-R;CPER;CPETR;CPETR1;WBSCR8;hCPE-R;claudin-4

Immunogen :A synthetic peptide of human CLDN4(NP_001296.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of HT-29 cells, using CLDN4 antibody .
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.