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CBX1 polyclonal antibody

货号: BS78309

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS78309

Product Name :CBX1 polyclonal antibody

Swiss-Prot :P83916

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:500 - 1:1000

Background :This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :21kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBX1;CBX;HP1-BETA;HP1Hs-beta;HP1Hsbeta;M31;MOD1;p25beta

Immunogen :A synthetic peptide of human HP1 beta/CBX1(NP_006798.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of OVCAR-3 cells, using CBX1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.