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NBS1/NBN polyclonal antibody

货号: BS78190

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS78190

Product Name :NBS1/NBN polyclonal antibody

Swiss-Prot :O60934

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IF/ICC IHC IP

Application_all :WB,1:500 - 1:1000|IF/ICC,1:100 - 1:500|IP,1:10 - 1:100|IHC,1:100 - 1:200

Background :Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NBS1/NBN polyclonal antibody detects endogenous levels of NBS1/NBN protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NBN; AT-V1; AT-V2; ATV; NBS; NBS1; P95; nibrin

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human NBS1/NBN.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Nibrin expression in HEK293T (A), A549 (B), Jurkat (C) whole cell lysates.

Immunohistochemical analysis of Nibrin staining in human lung cancer formalin fixed paraffin embedded tissue section.

免疫沉淀（IP）

免疫组织化学（IHC）