产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

ANK3 polyclonal antibody

货号: BS77975

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS77975

Product Name :ANK3 polyclonal antibody

Swiss-Prot :Q12955

Host :Rabbit

Reactivity :Human, Mouse

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MRT37; ANKYRIN-G

Immunogen :Recombinant fusion protein of human ANK3(NP_066267.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of SH-SY5Y cells using ANK3 Rabbit pAb at dilution of 1:150 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of Neuro-2a cells using ANK3 Rabbit pAb at dilution of 1:200 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）