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ATG4A polyclonal antibody（KU）

货号: BS7735

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS7735

Product Name :ATG4A polyclonal antibody（KU）

Swiss-Prot :Q8WYN0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB 1:1000 - 1:2000

Background :Autophagy, a process that results in the lysosomal-dependent degradation of cytosolic compartments, is carried out by the autophagosome, which is a double-membrane vesicle whose formation is catalyzed by several autophagy-related gene (Atg) proteins. Atg4a (ATG4 autophagy related 4 homolog A), also known as APG4A or AUTL2, is a 398 amino acid protein that localizes to the cytoplasm and belongs to the peptidase C54 family. Expressed in a variety of tissues, including brain, skeletal muscle and fetal liver, Atg4a functions as a cysteine protease that cleaves the C-terminal part of target proteins, such as GABARAP and MAP1LC3, and plays an essential role in autophagy. Atg4a exists as multiple alternatively spliced isoforms and is functionally inhibited by N-ethylmaleimide.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATG4A polyclonal antibody detects endogenous levels of ATG4A protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Apg4a; ATG4 autophagy related 4 homolog A (S. cerevisiae); ATG4A; ATG4A_HUMAN; Atg4al; AUT like 2 cysteine endopeptidase; AUT-like 2 cysteine endopeptidase; Autl2; Autophagin 2; Autophagin-2; Autophagy related 4A cysteine peptidase; Autophagy related cysteine endopeptidase 2; Autophagy related protein 4 homolog A; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; AV169859; Cysteine protease ATG4A; hAPG4A;

Immunogen :Recombination protein , corresponding to amino acids 38-186 of Human ATG4A.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of ATG4A pAb at 1:2000 dilution Lane1:CT26 whole cell lysate(20ug) Lane2:PC12 whole cell lysate(20ug) Lane3:HCT116 whole cell lysate(20ug) Lane4:PC3 whole cell lysate(20ug)