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Proteinase 3/PR3 polyclonal antibody

货号: BS77308

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS77308

Product Name :Proteinase 3/PR3 polyclonal antibody

Swiss-Prot :P24158

Host :Rabbit

Reactivity :Rat

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :25kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ACPA;AGP7;C-ANCA;CANCA;MBN;MBT;NP-4;NP4;P29;PR-3;PR3;PRTN3

Immunogen :Recombinant fusion protein of human Proteinase 3/PR3(NP_002768.3).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of Rat lung, using Proteinase 3/PR3 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 60s.