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RUNX1T1 polyclonal antibody

货号: BS77245

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS77245

Product Name :RUNX1T1 polyclonal antibody

Swiss-Prot :Q06455

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:200 - 1:1000

Background :This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :68KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RUNX1T1;AML1-MTG8;AML1T1;CBFA2T1;CDR;ETO;MTG8;ZMYND2

Immunogen :Recombinant fusion protein of human RUNX1T1(NP_783554.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of Rat brain, using RUNX1T1 antibody at 1:690 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 60s.