Product Name :SIDT2 polyclonal antibody
Application_all :IF/ICC,1:50 - 1:100
Background :Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA, a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded. Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis. In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA (500 - 700 base pairs, but not dsRNA shorter than 100 bp (By similarity.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Unmodification
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :SIDT2;CGI-40
Immunogen :Recombinant fusion protein of human SIDT2(NP_001035545.1).
Modification :Unmodification
