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PGRMC2 polyclonal antibody

货号: BS76687

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS76687

Product Name :PGRMC2 polyclonal antibody

Swiss-Prot :O15173

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity. May serve as a universal non-classical progesterone receptor in the uterus (Probable. Intracellular heme chaperone required for delivery of labile, or signaling heme, to the nucleus (By similarity. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat, which has a high demand for heme, delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :23kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PGRMC2;DG6;PMBP

Immunogen :A synthetic peptide of human PGRMC2(NP_006311.3).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of MCF-7 cells, using PGRMC2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 5min.

Immunofluorescence analysis of NIH/3T3 cells using PGRMC2 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.