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EDARADD polyclonal antibody

货号: BS76562

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS76562

Product Name :EDARADD polyclonal antibody

Swiss-Prot :Q8WWZ3

Host :Rabbit

Reactivity :Mouse, Rat

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :25kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EDARADD;ECTD11A;ECTD11B;ED3;EDA3

Immunogen :Recombinant fusion protein of human EDARADD(NP_665860.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of mouse pancreas, using EDARADD antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.