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ITGB3BP polyclonal antibody

货号: BS75994

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS75994

Product Name :ITGB3BP polyclonal antibody

Swiss-Prot :Q13352

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IHC

Application_all :IHC,1:50 - 1:200

Background :This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ITGB3BP;CENP-R;CENPR;HSU37139;NRIF3;TAP20

Immunogen :Recombinant fusion protein of human ITGB3BP(NP_055103.3).

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry of paraffin-embedded human liver using ITGB3BP antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded human appendix using ITGB3BP antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded human gastric cancer using ITGB3BP antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.

Immunohistochemistry of paraffin-embedded mouse brain using ITGB3BP antibody at dilution of 1:100 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.