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EWSR1 polyclonal antibody

货号: BS75549

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS75549

Product Name :EWSR1 polyclonal antibody

Swiss-Prot :Q01844

Host :Rabbit

Reactivity :Human

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:100

Background :This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EWSR1;EWS;EWS-FLI1;bK984G1.4

Immunogen :Recombinant fusion protein of human EWSR1(NP_001156757.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of U2OS cells using EWSR1 antibody .