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IFIT2 polyclonal antibody

货号: BS75447

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS75447

Product Name :IFIT2 polyclonal antibody

Swiss-Prot :P09913

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism. Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IFIT2 polyclonal antibody detects endogenous levels of IFIT2 protein.

BiowMW :50kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :IFIT2;G10P2;GARG-39;IFI-54;IFI-54K;IFI54;IFIT-2;ISG-54 K;ISG-54K;ISG54;P54;cig42

Immunogen :Recombinant fusion protein of human IFIT2(NP_001538.4).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of IFIT2 expression in HepG2 (A) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）