产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

CWC22 polyclonal antibody

货号: BS75186

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS75186

Product Name :CWC22 polyclonal antibody

Swiss-Prot :Q9HCG8

Host :Rabbit

Reactivity :Mouse

Applications :WB

Application_all :WB,1:1000 - 1:2000

Background :Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :110kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CWC22;EIF4GL;NCM;fSAPb

Immunogen :Recombinant fusion protein of human CWC22(NP_065994.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using CWC22 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.

CWC22-Mediated Alternative Splicing of Spp1 Regulates Nociception in Inflammatory Pain

JournalNEUROSCIENCE

ApplicationWB

IF3.3

SpeciesMouse

PMID37838283