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PACS1 polyclonal antibody

货号: BS74959

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS74959

Product Name :PACS1 polyclonal antibody

Swiss-Prot :Q6VY07

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:1000 - 1:3000

Background :This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :105kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PACS1;MRD17;SHMS

Immunogen :Recombinant fusion protein of human PACS1(NP_060496.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of 293T cells, using PACS1 antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 10s.