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Caspase-10 polyclonal antibody

货号: BS74250

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS74250

Product Name :Caspase-10 polyclonal antibody

Swiss-Prot :Q92851

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :IF/ICC

Application_all :IF/ICC,1:50 - 1:200

Background :This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CASP10;ALPS2;FLICE2;MCH4;caspase-10

Immunogen :Recombinant fusion protein of human Caspase-10(NP_116759.2).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of HeLa cells using Caspase-10 Polyclonal Antibody at dilution of 1:100 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）