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BCL2A1 polyclonal antibody

货号: BS74245

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS74245

Product Name :BCL2A1 polyclonal antibody

Swiss-Prot :Q16548

Host :Rabbit

Reactivity :Human

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Unmodification

BiowMW :Refer to figures

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BCL2A1;ACC-1;ACC-2;ACC1;ACC2;BCL2L5;BFL1;GRS;HBPA1

Immunogen :A synthetic peptide of human BCL2A1(NP_004040.1).

Conjugate :Unconjugated

Modification :Unmodification

Immunofluorescence analysis of Jurkat cells using BCL2A1 Rabbit pAb at dilution of 1:250 . Blue: DAPI for nuclear staining.

Immunofluorescence analysis of THP-1 cells using BCL2A1 Rabbit pAb at dilution of 1:250 . Blue: DAPI for nuclear staining.

免疫沉淀（IP）

免疫组织化学（IHC）