Product Name :Phospho-AKT2 specific-S474 polyclonal antibody
Reactivity :Human, Mouse, Rat
Application_all :WB,1:500 - 1:2000
Background :This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Phosphorylated
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :AKT2;HIHGHH;PKBB;PKBBETA;PRKBB;RAC-BETA
Immunogen :A synthetic phosphorylated peptide around S474 of human AKT2 specific.
Modification :Phosphorylated
