Product Name :Phospho-TrkB-Y816 polyclonal antibody
Application_all :WB,1:500 - 1:2000
Background :This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Phosphorylated
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NTRK2;GP145-TrkB;TRKB;trk-B;TrkB;OBHD
Immunogen :A synthetic phosphorylated peptide around Y816 of human TrkB(NP_001018074.1).
Modification :Phosphorylated
