Product Name :Phospho-MEK7-S271/T275 polyclonal antibody
Application_all :WB,1:500 - 1:2000
Background :The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Phosphorylated
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :MAP2K7;JNKK2;MAPKK7;MEK;MEK 7;MKK7;PRKMK7;SAPKK-4;SAPKK4;MEK7;MKK7
Immunogen :A synthetic phosphorylated peptide around S271 & T275 of human MEK7(NP_660186.1).
Modification :Phosphorylated
