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CBFA2T3 polyclonal antibody

货号: BS72475

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS72475

Product Name :CBFA2T3 polyclonal antibody

Swiss-Prot :O75081

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :75KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CBFA2T3;ETO2;MTG16;MTGR2;RUNX1T3;ZMYND4

Immunogen :Recombinant fusion protein of human CBFA2T3(NP_005178.4).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of various lysates, using CBFA2T3 antibody at 1:440 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 180s.