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Casein Kinase IIα polyclonal antibody

货号: BS72321

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS72321

Product Name :Casein Kinase IIα polyclonal antibody

Swiss-Prot :P68400

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, e and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Casein Kinase IIα polyclonal antibody detects endogenous levels of Casein Kinase IIα protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Epigenetic Writers and Erasers of Histones H2A H2B and H4,

Alternative Name :CK II; CKII alpha; 1457; CSNK2A1; CK2A1; CKII; CKII alpha; Casein kinase II subunit alpha; Casein Kinase IIα; CKIIα; CK-IIα; CKII-α; CK IIα; CKII α; CKIIα;

Immunogen :Recombinant protein of human CSNK2A1

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using CSNK2A1 antibody.