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CLN5 polyclonal antibody（KU）

货号: BS72228

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS72228

Product Name :CLN5 polyclonal antibody（KU）

Swiss-Prot :O75503

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC

Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200

Background :This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :~ 47 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CLN5;NCL

Immunogen :Recombinant fusion protein of human CLN5(NP_006484.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of CLN5 pAb at 1:500 dilution Lane1:PMVEC whole cell lysate(40ug) Lane2:AML-12 whole cell lysate(40ug) Lane3:L02 whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug)

Immunohistochemistry of paraffin-embedded human appendix using CLN5 antibody at dilution of 1:150 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.