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Dopamine Receptor D3 (DRD3) polyclonal antibody

货号: BS7107

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS7107

Product Name :Dopamine Receptor D3 (DRD3) polyclonal antibody

Swiss-Prot :P35462

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IF/ICC

Application_all :WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

Background :This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :44kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DRD3;D3DR;ETM1;FET1

Immunogen :Recombinant fusion protein of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3))(NP_000787.2).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of mouse brain, using Dopamine Receptor D3 ) antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

Immunofluorescence analysis of U2OS cells using Dopamine Receptor D3 ) antibody . Blue: DAPI for nuclear staining.