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ATG4D polyclonal antibody（KU）

货号: BS70951

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS70951

Product Name :ATG4D polyclonal antibody（KU）

Swiss-Prot :Q86TL0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB 1:500 - 1:2000

Background :Atg4D (autophagy-related gene 4D), also known as APG4D or AUTL4, is a 474 amino acid protein that localizes to the cytoplasm and belongs to the C-54 family of cysteine proteases. Expressed predominately in skeletal muscle, but also present in testis, Atg4D functions as a cysteine protease that is required for autophagy and functions to specifically cleave the C-terminal region of target proteins, thereby allowing the target proteins to bind to autophagosomes. The enzymatic activity of Atg4D is inhibited by Nethylmaleimide, a thiol reactive compound that is capable of modifying cystine residues in proteins and peptides.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :ATG4D polyclonal antibody detects endogenous levels of ATG4D protein.

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :APG4D; AUTL4; APG4-D;

Immunogen :Recombination protein, corresponding to amino acids 123-474 of Human ATG4D.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ATG4D pAb at 1:1000 dilution Lane1:The Lung tissue lysate of Mouse(40ug) Lane2:The Lung tissue lysate of Rat(40ug) Lane3:H1792 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug)