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[KO Validated] Integrin alpha 2 (ITGA2/CD49b) polyclonal antibody

货号: BS70832

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70832

Product Name :[KO Validated] Integrin alpha 2 (ITGA2/CD49b) polyclonal antibody

Swiss-Prot :P17301

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC IF/ICC IP

Application_all :WB: 1:500~1:2000 IHC: 1:50~1:200 IF/ICC: 1:50~1:200 IP: 1:50~1:100

Background :This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Integrin alpha 2 polyclonal antibody detects endogenous levels of Integrin alpha 2 protein.

BiowMW :150KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CD49B; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Integrin alpha 2 (ITGA2/CD49b).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of Integrin alpha 2 (ITGA2/CD49b) expression in NIH3T3 (A) whole cell lysates.

Immunohistochemical analysis of Integrin alpha 2 (ITGA2/CD49b) staining in human colon cancer formalin fixed paraffin embedded tissue section.

Quantitative proteomics reveals potential anti-inflammatory protein targets of radial extracorporeal shock wave therapy in TNF-α-induced model of acute inflammation in primary human tenocytes

JournalHeliyon

ApplicationWB

IF3.776

SpeciesHuman

PMID36506366