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ALKBH7 polyclonal antibody

货号: BS70810
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS70810
Product Name :ALKBH7 polyclonal antibody
Swiss-Prot :Q9BT30
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB
Application_all :WB,1:200 - 1:2000
Background :May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro, but this activity may be due to the absence of the true substrate. Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism (By similarity.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
BiowMW :26-30kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :ALKBH7;ABH7;SPATA11;UNQ6002
Immunogen :Recombinant fusion protein of human ALKBH7(NP_115682.1).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of various cell lines, using ALKBH7 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com