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TRIB1 polyclonal antibody

货号: BS70782

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS70782

Product Name :TRIB1 polyclonal antibody

Swiss-Prot :Q96RU8

Host :Rabbit

Reactivity :Human

Applications :WB

Application_all :WB,1:1000 - 1:4000

Background :Adapter protein involved in protein degradation by interacting with COP1 ubiquitin ligase. The COP1-binding motif is masked by autoinhibitory interactions with the protein kinase domain. Serves to alter COP1 substrate specificity by directing the activity of COP1 toward CEBPA. Binds selectively the recognition sequence of CEBPA. Regulates myeloid cell differentiation by altering the expression of CEBPA in a COP1-dependent manner (By similarity. Controls macrophage, eosinophil and neutrophil differentiation via the COP1-binding domain (By similarity. Interacts with MAPK kinases and regulates activation of MAP kinases, but has no kinase activity.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :38kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TRIB1;C8FW;GIG-2;GIG2;SKIP1;TRB-1;TRB1

Immunogen :Recombinant fusion protein of human TRIB1(NP_079471.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using TRIB1 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 5s.