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LXRα polyclonal antibody

货号: BS6785
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS6785
Product Name :LXRα polyclonal antibody
Swiss-Prot :Q13133
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB
Application_all :WB,1:500 - 1:2000
Background :The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
BiowMW :50KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :NR1H3;LXR-a;LXRA;RLD-1;LXR alpha
Immunogen :Recombinant fusion protein of human LXRα(NP_005684.2).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of extracts of HepG2 cells, using LXRα antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.
Western blot analysis of extracts of Mouse kidney, using LXRα antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 90s.
  • Pomegranate peel polyphenols inhibit lipid accumulation and enhance cholesterol efflux in raw264.7 macrophages
    JournalFood & Function
    ApplicationWB
    IF5.396
    SpeciesHuman
  • Pomegranate punicalagin inhibits the foam cells formation in Raw264.7 macrophages
    JournalFood Science and Technology
    ApplicationWB
    IF2.602
    SpeciesMouse
    PMID

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com