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LKB1 polyclonal antibody

货号: BS6740
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS6740
Product Name :LKB1 polyclonal antibody
Swiss-Prot :Q15831
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, IF/ICC
Application_all :WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:200
Background :This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Polyclonal Antibodies
BiowMW :49-60KDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :LKB1;PJS;hLKB1;STK11
Immunogen :Recombinant fusion protein of human LKB1(NP_000446.1).
Conjugate :Unconjugated
Modification :Unmodification
Western blot analysis of various lysates, using LKB1 antibody at 1:690 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.
Western blot analysis of Mouse heart, using LKB1 antibody at 1:690 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 30s.
Immunohistochemistry of paraffin-embedded human lung cancer using LKB1 Rabbit pAb at dilution of 1:50 .Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Immunofluorescence analysis of NIH/3T3 cells using LKB1 Rabbit pAb at dilution of 1:50 . Blue: DAPI for nuclear staining.
  • Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes
    JournalInternational Journal Of Biochemistry & Cell Biology
    ApplicationWB,IF
    IF3.144
    SpeciesMouse
    PMID
  • Decreased Expression of LKB1 Correlates with Poor Prognosis in Hepatocellular Carcinoma Patients Undergoing Hepatectomy
    JournalAsian Pacific Journal of Cancer Prevention
    ApplicationIHC
    IF0
    SpeciesHuman

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com