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CCL25 polyclonal antibody

货号: BS6651

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6651

Product Name :CCL25 polyclonal antibody

Swiss-Prot :O15444

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC-P

Application_all :WB: 1:500~1:1000 IHC-P: 1:100~1:500

Background :Chemokines are likely to play an important role in regulating the trafficking of developing T cells within the thymus. Chemokine C-C thymus expressed chemokine (TECK), also designated chemokine ligand 25 (CCL25), small induc-ible cytokine A25, chemokine b-15 or CK b-15, is expressed predominantly in thymic dendritic cells, thymic epithelial cells and in the small intestine. TECK, a CCR9 ligand, has suppressive activity against immature subsets of myeloid progenitors which have been stimulated to proliferate by multiple growth factors. TECK delivers signals through CCR9, which is important for the nav-igation of developing thymocytes. Bone marrow pre-pro-B cells and cells capable of generating pro-B colonies in the presence of interleukin-7 and Flt-3 ligand migrate to TECK, a response lost in later stages of B cell development.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CCL25 polyclonal antibody detects endogenous levels of CCL25 protein.

BiowMW :~ 17 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :C-C motif chemokine 25; Chemokine TECK; Small-inducible cytokine A25; Thymus-expressed chemokine; CCL25; SCYA25; TECK

Immunogen :A synthetic peptide corresponding to a sequence within amino acids 50-150 of human CCL25 (NP_001381563.1).

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of lysates from wild type (WT) and 293T cells transfected with CCL25 using CCL25 pAb at 1:1000 dilution.

Immunohistochemistry analysis of CCL25 in paraffin-embedded Mouse large intestine tissue using CCL25 pAb at a dilution of 1:300 (40x lens).

Immunohistochemistry analysis of CCL25 in paraffin-embedded Rat large intestine tissue using CCL25 pAb at a dilution of 1:300 (40x lens).

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