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MHC class I Recombinant Rabbit mAb

货号: BS66218

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66218

Product Name :MHC class I Recombinant Rabbit mAb

Swiss-Prot :P30443; P01889; P01891; P01892; P13746; P16188; P30450

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB,1:500 - 1:1000

Background :The human leukocyte antigen (HLA) system is a gene complex encoding the major histocompatibility complex (MHC) proteins in humans. These cell surface proteins are responsible for the regulation of antigen-specific immunity in humans. HLA genes are highly polymorphic, allowing them to fine-tune the adaptive immune response. HLAs corresponding to MHC class I (HLA-A, B, and C) present small peptide antigens from inside the cell, approximately 8 to 10 amino acids in length, to CD8+ T lymphocytes in order to activate a cytotoxic T cell response. HLAs corresponding to MHC class II (HLA-DP, DM, DO, DQ, and DR) present antigens from outside of the cell, approximately 15 to 24 residues in length, to CD4+ T helper cells, which in turn secrete cytokines and stimulate B cells to produce antibodies to that specific antigen. HLAs corresponding to MHC class III encode components of the complement system.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from cell culture supernatant by protein A+G and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MHC class I mAb detects endogenous levels of MHC class I protein.

Note :~ 41 kDa

Pathway :For research use only, not for use in diagnostic procedure.

Alternative Name :HLAA; HLA class I histocompatibility antigen, A-1 alpha chain; MHC class I antigen A*1; HLAB; HLA class I histocompatibility antigen, B-7 alpha chain; MHC class I antigen B*7; HLAA; HLA class I histocompatibility antigen, A-68 alpha chain; Aw-68; HLA class I histocompatibility antigen, A-28 alpha chain; MHC class I antigen A*68; HLAA; HLA class I histocompatibility antigen, A-2 alpha chain; MHC class I antigen A*2; HLAA; HLA class I histocompatibility antigen, A-11 alpha chain; MHC class I antigen A*11; HLAA; HLA class I histocompatibility antigen, A-30 alpha chain; MHC class I antigen A*30; HLAA; HLA class I histocompatibility antigen, A-26 alpha chain; MHC class I antigen A*26

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within human MHC class I.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of MHC class I expression in HEK293T (A), H1792 (B), HCT116 (C), mouse brain (D), mouse kidney (E), rat brain (F), rat kidney (G) whole cell lysates.