产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

GLP-1R polyclonal antibody

货号: BS66214

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS66214

Product Name :GLP-1R polyclonal antibody

Swiss-Prot :P43220

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC IF/ICC

Application_all :WB: 1:500~1:1000IHC: 1:100~1:200IF/ICC: 1:100~1:500

Background :This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :GLP-1R polyclonal antibody detects endogenous levels of GLP-1R protein.

Note :53kDa

Pathway :For research use only, not for use in diagnostic procedure.

Alternative Name :GLP1R;GLP-1;GLP-1-R;GLP-1R

Immunogen :KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GLP-1R.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of GLP-1R expression in Hela (A), mouse brain (B), rat brain (C) whole cell lysates.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）