Product Name :GLS polyclonal antibody
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, IF/ICC
Application_all :WB: 1:500~1:1000
IHC: 1:50~1:200
IF/ICC: 1:50~1:200
Background :Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers.
Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :GLS pAb detects endogenous levels of GLS protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :GLS1; KIAA0838; Glutaminase kidney isoform mitochondrial; GLS; K-glutaminase; L-glutamine amidohydrolase
Immunogen :Recombinant full length protein of human GLS
