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Calumenin polyclonal antibody

货号: BS6483

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS6483

Product Name :Calumenin polyclonal antibody

Swiss-Prot :O43852

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB,IHC,IF

Application_all :WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background :Caluminin is a 315 amino acid Ca2+-binding member of the CREC, EF-hand protein family. Calumenin is a secreted protein t hat contains six Ca2+-binding (EF-hand) motifs and is expressed in the lumen of the endoplasmic reticulum (ER) and Golgi apparatus. In the presence of Ca2+, Calumenin interacts with serum amyloid P component (SAP) and, together, they may play a role in the immunological defense system and participate in amyloidosis, the pathological formation of amyloid deposits in different types of tissues. Calumenin has an inhibitory effect on the vitamin K-dependent g-carboxylation system which converts vitamin K-dependent proteins to Gla-containing proteins. Calumenin may also be involved in the pathophysiology of thrombosis and/or wound healing by acting in an autocrine or paracrine manner.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CALU polyclonal antibody detects endogenous levels of CALU protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Calumenin; Crocalbin; IEF SSP 9302; CALU

Immunogen :Recombinant full length Human CALU.

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cells, using CALU antibody.

Immunohistochemistry of paraffin-embedded mouse skin using CALU antibody at dilution of 1:100 (x40 lens).

Immunohistochemistry of paraffin-embedded rat lung using CALU antibody at dilution of 1:100 (x40 lens).

免疫沉淀（IP）