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PCNA polyclonal antibody

货号: BS6438

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS6438

Product Name :PCNA polyclonal antibody

Swiss-Prot :P12004

Host :Rabbit

Reactivity :Human, Mouse, Rat,African green monkey

Applications :WB

Application_all :WB,1:500 - 1:2000

Background :The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Product :1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Polyclonal Antibodies

BiowMW :34KDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PCNA;ATLD2

Immunogen :A synthetic peptide of human PCNA(NP_002583.1).

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts of various cell lines, using PCNA antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit .
Exposure time: 3s.

Chemopreventive activity of GEN-27, a genistein derivative, in colitis-associated cancer is mediated by p65-CDX2-β-catenin axis

JournalOncotarget

ApplicationWB

IF0

SpeciesHuman

PMID26910375
Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma

JournalBMC CANCER

ApplicationWB

IF3.8

SpeciesHuman

PMID37697240
JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation

JournalBMC GENOMICS

ApplicationWB,IHC

IF4.4

SpeciesMouse

PMID38424516