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BLK (phospho-Y389) polyclonal antibody

货号: BS64159

价格：￥ 1350

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS64159

Product Name :BLK (phospho-Y389) polyclonal antibody

Swiss-Prot :P51451

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development. Activation of B cells by various ligands is accompanied by activation of Blk. It has been suggested that Blk is involved in the control of B cell differentiation and proliferation. Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis. Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :BLK (phospho-Y389) polyclonal antibody detects endogenous levels of BLK protein only when phosphorylated at Tyr389 .

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk; BLK

Immunogen :Synthetic phosphopeptide derived from human BLK around the phosphorylation site of Tyrosine389.

Conjugate :Unconjugated

Modification :Phosphorylation

Western blot (WB) analysis of BLK (phospho-Y389) polyclonal antibody at 1:500 dilution Lane1:COS-7whole cell lysate(40ug) Lane2:MCF-7whole cell lysate(40ug) Lane3:CT26 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug)